Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun Any of several small, basic proteins most commonly found in association with the DNA in the chromatin of eukaryotes.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biochemistry Any of various simple water soluble proteins that are rich in the basic amino acids lysine and arginine and are complexed with DNA in the nucleosomes of eukaryotic chromatin.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • noun a simple protein containing mainly basic amino acids; present in cell nuclei in association with nucleic acids

Etymologies

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Examples

  • There is a sophisticated code, known as the histone code, that directs the decisions as to which parts of the DNA sequence are transcribed into mRNA and which are not.

    The Chemistry of Calm M.D. Henry Emmons 2010

  • Typically, the gossamer thread of DNA is wound around a spool of protein called histone; when this second class of enzymes strips away part of the packaging, the DNA becomes so tightly wound up that it can't loosen up enough to be read by the cell.

    Beyond the Book of Life 2009

  • A group of agents called histone deacetylase inhibitors can help here, says Sharon Lewin, director of the infectious-diseases unit at Alfred Hospital in Melbourne, who is about to start a clinical trial of a histone-deacetylase inhibitor called SAHA.

    The Economist: Daily news and views 2011

  • "In addition to this, we have also shown that when the neuroblastoma and breast cancer cells are treated with a new class of anti-cancer drugs called histone deacetylase inhibitors (HDACIs), they are able to turn the TG2 gene back on, which then inhibits tumour growth."

    WN.com - Articles related to Mothers working part-time have healthiest kids: study 2010

  • "In addition to this, we have also shown that when the neuroblastoma and breast cancer cells are treated with a new class of anti-cancer drugs called histone deacetylase inhibitors (HDACIs), they are able to turn the TG2 gene back on, which then inhibits tumour growth."

    WN.com - Articles related to Mothers working part-time have healthiest kids: study 2010

  • While they are powerful killers of some breast cancer cells, new drugs called histone deacetylase inhibitors, or HDAC inhibitors, also increase self-digestion, or autophagy, in surviving, mega-stressed cells.

    Gaea Times (by Simple Thoughts) Breaking News and incisive views 24/7 Ani 2010

  • While they are powerful killers of some breast cancer cells, new drugs called histone deacetylase inhibitors, or HDAC inhibitors, also increase self-digestion, or autophagy, in surviving, mega-stressed cells.

    Gaea Times (by Simple Thoughts) Breaking News and incisive views 24/7 Ani 2010

  • "In addition to this, we have also shown that when the neuroblastoma and breast cancer cells are treated with a new class of anti-cancer drugs called histone deacetylase inhibitors (HDACIs), they are able to turn the TG2 gene back on, which then inhibits tumour growth."

    WN.com - Articles related to Mothers working part-time have healthiest kids: study 2010

  • While they are powerful killers of some breast cancer cells, new drugs called histone deacetylase inhibitors, or HDAC inhibitors, also increase self-digestion, or autophagy, in surviving, mega-stressed cells.

    Gaea Times (by Simple Thoughts) Breaking News and incisive views 24/7 Ians 2010

  • While they are powerful killers of some breast cancer cells, new drugs called histone deacetylase inhibitors, or HDAC inhibitors, also increase self-digestion, or autophagy, in surviving, mega-stressed cells.

    Gaea Times (by Simple Thoughts) Breaking News and incisive views 24/7 Ians 2010

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