Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biochemistry, genetics A folded protein domain that binds to DNA and has a function in transcription

Etymologies

from Wiktionary, Creative Commons Attribution/Share-Alike License

homeo- +‎ domain

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Examples

  • These are the Hox genes; they are recognizable by virtue of the presence of a 60 amino acid long DNA binding region called the homeodomain, by similarities in sequence, by their role as regulatory genes expressed early in development, by the restriction of their expression to bands of tissue, by their clustering in the genome to a single location, and by the remarkable collinearity of their organization on the chromosome to their pattern of expression: the order of the gene's position in the cluster is related to their region of expression along the length of the animal.

    Hox genesis - The Panda's Thumb 2005

  • These are the Hox genes; they are recognizable by virtue of the presence of a 60 amino acid long DNA binding region called the homeodomain, by similarities in sequence, by their role as regulatory genes expressed early in development, by the restriction of their expression to bands of tissue, by their clustering in the genome to a single location, and by the remarkable collinearity of their organization on the chromosome to their pattern of expression: the order of the gene's position in the cluster is related to their region of expression along the length of the animal.

    The Panda's Thumb: December 2005 Archives 2005

  • One possible candidate for such front-loaded ˜information 'would be the homeodomain proteins.

    2007 September - Telic Thoughts 2007

  • Subsequent work has shown that homeodomain helix-turn-helix motifs are somewhat different from bacterial ones Branden, C., and Tooze, J.1999.

    The Edge of Evolution Michael J. Behe 2007

  • Subsequent work has shown that homeodomain helix-turn-helix motifs are somewhat different from bacterial ones Branden, C., and Tooze, J.1999.

    The Edge of Evolution Michael J. Behe 2007

  • Subsequent work has shown that homeodomain helix-turn-helix motifs are somewhat different from bacterial ones Branden, C., and Tooze, J.1999.

    The Edge of Evolution Michael J. Behe 2007

  • Subsequent work has shown that homeodomain helix-turn-helix motifs are somewhat different from bacterial ones Branden, C., and Tooze, J.1999.

    The Edge of Evolution Michael J. Behe 2007

  • Antennapedia homeodomain and its complex with the operator

    Kurt Wüthrich - Autobiography 2003

  • We have identified the PWWP domain of bromo and plant homeodomain (PHD) finger-containing protein 1 (BRPF1) as a H3K36me3 binding module and have determined the structure of this domain in complex with an H3K36me3-derived peptide.

    Naturejobs - All Jobs Alessandro Vezzoli 2010

  • CLV3 dependent activation of the two receptor systems represses the expression of WUSCHEL (WUS), a homeodomain transcription factor that is normally produced from OC cells, and which is required for the maintenance of stem cells

    PLoS ONE Alerts: New Articles Tim Hohm et al. 2010

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