Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun genetics Any agent that causes
hypermutation
Etymologies
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Examples
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Thus, patients who initially respond to temozolomide may evolve not only treatment resistance but also a hypermutator phenotype (since DNA repair genes have been mutated).
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By integrating methylation data, somatic mutation data and clinical treatment data, scientists identified a relationship between MGMT methylation and a hypermutator phenotype described previously [6].
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