Definitions
from The American Heritage® Dictionary of the English Language, 5th Edition.
- noun A tricyclic compound, C19H24N2, used to treat depression and enuresis.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun chemistry a
tricyclic heterocyclic compound used to treatdepression
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- noun a tricyclic antidepressant (trade names Imavate and Tofranil) used to treat clinical depression
Etymologies
from The American Heritage® Dictionary of the English Language, 4th Edition
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Examples
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His data was overwhelming, his enthusiasm even stronger, but G22355—by then known as imipramine—was hardly taking the world by storm, and Kuhn was roundly ignored.
MANUFACTURING DEPRESSION Gary Greenberg 2010
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Finally, he experienced some relief when he switched to an old-fashioned tricyclic antidepressant called imipramine.
The Full Feed from HuffingtonPost.com M.D. Carol W. Berman 2011
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The other showed that an antidepressant called imipramine, which was known to block NPC1, seemed to prevent infection as well.
NYT > Home Page By AMANDA SCHAFFER 2012
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A class of older antidepressants called tricyclics, such as amitriptyline (Elavil) or imipramine (Tofranil), are effective at staving off chronic tension-type headaches in many people who have not found relief with over-the-counter medications.
Case of the Daily Headache Melinda Beck 2011
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This “vital disturbance,” Kuhn claimed, is what imipramine was uniquely suited to treat.
MANUFACTURING DEPRESSION Gary Greenberg 2010
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Endogenous depression was exactly the disease that imipramine cured, and the proof that you had been sick was that imipramine cured you.
MANUFACTURING DEPRESSION Gary Greenberg 2010
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The studies showed that this was true, whether or not the patients took Paxil, a selective serotonin reuptake inhibitor (SSRI), or imipramine, a tricylcic, an older generation of anti-depressant medication.
Robert David Jaffee: Medication Can Help The Severely Depressed 2010
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And when Axelrod showed that imipramine worked the latter way, blocking the reuptake of norepinephrine, it was easy to believe that the catecholamine hypothesis was correct.
MANUFACTURING DEPRESSION Gary Greenberg 2010
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Amphetamines only made you feel better, but imipramine made you feel well—which meant that you must have been sick all along.
MANUFACTURING DEPRESSION Gary Greenberg 2010
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At a time when psychoanalysis was the mainstay of psychiatry, he was arguing that imipramine could “bring a complete change in the situation within a few days, which could not be achieved by intensive prolonged psychotherapy.”
MANUFACTURING DEPRESSION Gary Greenberg 2010
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