Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biochemistry Any of many
heterodimeric transmembrane proteins that function asreceptors incommunication betweencells .
Etymologies
Sorry, no etymologies found.
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Examples
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In addition, Merck is developing cilengitide, which is the first in a new class of investigational anti-cancer therapies called integrin inhibitors to reach Phase III of development; it is currently being investigated for the treatment of glioblastoma, SCCHN and NSCLC.
TradingMarkets 2010
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In addition, Merck is developing cilengitide, which is the first in a new class of investigational anti-cancer therapies called integrin inhibitors to reach Phase III of development; it is currently being investigated for the treatment of glioblastoma,
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In addition, Merck is developing cilengitide, which is the first in a new class of investigational anti-cancer therapies called integrin inhibitors to reach Phase III of development; it is currently being investigated for the treatment of glioblastoma, SCCHN and NSCLC.
TradingMarkets 2010
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Through their study, they identified a molecule - called LXY1 - that binds with high specificity to a particular cell-surface protein called alpha-3 integrin, which is overexpressed on cancer cells.
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Through their study, they identified a molecule - called LXY1 - that binds with high specificity to a particular cell-surface protein called alpha-3 integrin, which is overexpressed on cancer cells.
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Together, these molecules, called integrin and netrin, may be a valuable new target in the efforts to halt cancer's spread via metastasis.
THE MEDICAL NEWS 2009
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Nature Medicine on 22 March, suggested that such effects might also occur for a class of drugs called integrin inhibitors.
Latest Articles 2009
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More specifically, they found that release of growth factor by GPR30 required the activation of a latent adhesion receptor (known as integrin 51).
Emaxhealth 2009
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On the other hand, the significance of a complex control of NFAT5 subcellular localization in isotonic conditions might be found outside hypertonic stress responses, since this factor can also regulate osmotic stress-unrelated processes, such as integrin-induced migration, cell differentiation and viral replication The sustained association of NFAT5 with chromatin through mitosis and interphase caused by deletion of its CTD was consistent with the high stability of NFAT5-DNA complexes described previously in vitro
PLoS ONE Alerts: New Articles Anaïs Estrada-Gelonch et al. 2009
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Likewise, choanoflagellates have five immunoglobulin domains, though they have no immune system; collagen, integrin and cadherin domains, though they have no skeleton or matrix binding cells together; and proteins called tyrosine kinases that are a key part of signaling between cells, even though Monosiga is not known to communicate, or at least does not form colonies.
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