iodoacetate

Na iodoacetate treatment eliminated selective absorption and Verzar had deduced that the selectivity was based on phosphorylation.

Sir James W. Black - Autobiography 1989

Garry's research student was showing that iodoacetate destroyed the intestinal epithelium, I wondered if iodoacetate was a general poison.

Sir James W. Black - Autobiography 1989

When I developed the technology to show that, in rats, iodoacetate rapidly and irreversibly reduced the blood pressure to about 40 mm Hg, I was faced with the question which has influenced my thinking ever since: when and to what extent does local blood flow act as a metabolic throttle?

Sir James W. Black - Autobiography 1989

If sodium iodoacetate is used instead of sodium chloroacetate, how will the rate of reaction be affected?

Yahoo! Answers: Latest Questions 2009

[1] Zn2+ [1] iodoacetate (, partial inhibition) [1] sodium dithionite

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(5 mM, 43% inhibition [1]) [1] iodoacetate (5 mM, 23% inhibition [1]) [1] m-hydroxybenzoate

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(48% inhibition at 1 mM [2]) [2, 10] Zn2+ [10] iodoacetate

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(40% inhibition compared to the activity without any metal [2]) [2] iodoacetate

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[1] acriflavin [1] diethyldithiocarbaminate (, inhibitory only after prolonged incuba - tion time) [1] iodoacetate

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[1] iodoacetate [1] NEM [1] p-hydroxymercuribenzoate

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