Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biochemistry A
diagram showing the varyingsubstrate andinhibitor concentrations that giveconstant enzyme activity
Etymologies
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Examples
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Synergism was determined by isobologram analysis of dose-response curves for cells exposed to varying concentrations of GSI (compound E, Axxora, San Diego, CA), dexamethasone (Sigma), and/or Notch1 inhibitory antibodies.
PLoS ONE Alerts: New Articles Miguel Aste-Amézaga et al. 2010
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E9 Dose of drug B E6 5 3 E3 1 1 3 5 7 9 Dose of drug A Figure 20.3 Classical isobologram for a synergistic or potentiating drug interaction.
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The isobologram has contours that are par - 5 allel line segments (see Figure 20.1).
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The contours Dose of drug A of the isobologram are convex away from the ori - gin of the plot (Figure 20.2).
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