kallikrein

The proposed treatment, ecallantide, is designed to partly block an enzyme known as kallikrein involved with the disorder.

FDA Questions Effectiveness of Dyax Drug for Rare Disorder 2009

Aspirin interferes with chemical mediators of kallikrein system.

Aspirin: effects, poisoning 2010

The researchers found that a combination of high blood sugar and plasma kallikrein resulted in increased bleeding.

BBC News - Home 2011

The group then studied the impact of a protein, plasma kallikrein, which had already been linked to sight problems in diabetics.

BBC News - Home 2011

Omeros' proprietary antifibrinolytic agents are highly selective inhibitors of plasmin, the enzyme responsible for fibrinolysis and dissolving blood clots, while avoiding significant inhibition of Factor XIa and kallikrein.

Omeros Licenses Novel Antifibrinolytic Agents - Yahoo! Finance 2011

Further, Trasylol® was non-selective and inhibited many proteins in addition to plasmin, including Factor XIa and kallikrein, important regulators of the coagulation cascade.

Omeros Licenses Novel Antifibrinolytic Agents - Yahoo! Finance 2011

They believe plasma kallikrein slows clotting when there is lots of sugar in the blood, although the exact mechanism remains unclear.

BBC News - Home 2011

Omeros' agents are designed to selectively inhibit plasmin, the enzyme responsible for fibrinolysis and dissolving blood clots, while avoiding significant inhibition of Factor XIa and kallikrein, important regulators of the coagulation cascade.

Omeros Licenses Novel Antifibrinolytic Agents - Yahoo! Finance 2011

"Biomarkers such as IGF or kallikrein family members might improve sensitivity and specificity," he concludes.

PhysOrg.com - latest science and technology news stories 2010

"Biomarkers such as IGF or kallikrein family members might improve sensitivity and specificity," he concludes.

PhysOrg.com - latest science and technology news stories 2010