ligand-binding

Services include validating and performing ligand-binding assays for novel clinical biomarkers, immunogenicity testing, cell-based assay testing and multiplex testing.

unknown title 2011

Averaging the individual dissociation constants, determined by fitting the data to a single-site ligand-binding model (SigmaPlot), gives a

Naturejobs - All Jobs Alessandro Vezzoli 2010

This leads to a simple analytical form for the ligand-dependent free energy per ligand-binding subunit, and KI are the ligand dissociation constants for the active and inactive states of the oligomer, respectively.

Naturejobs - All Jobs Thomas S Shimizu 2010

Services include validating and performing ligand-binding assays for novel clinical biomarkers, immunogenicity testing, cell based assay testing and multiplex testing.

The Earth Times Online Newspaper 2010

SELEX is a well established in vitro selection tool to analyze the structure of ligand-binding nucleic acid sequences called aptamers.

Elites TV PLoS ONE 2010

A comparison of the signalling mechanisms of mammalian and insect receptors has revealed an unexpected functional distinction: mammals rely almost exclusively on metabotropic ligand-binding receptors, which use second messenger signalling cascades to indirectly activate ion channels, whereas insects use ionotropic receptors, which are gated directly by chemical stimuli, thereby leading to neuronal depolarization.

Naturejobs - All Jobs Ana Florencia Silbering 2010

Brown, paired DNA-binding domains; cyan and blue, paired ligand-binding domains.

Naturejobs - All Jobs Darcie J Miller 2010

With the classical, active-site oriented drug-development approach reaching its limits, protein ligand-binding sites in general and allosteric sites in particular are increasingly attracting the interest of medicinal chemists in the search for new types of targets and strategies to drug development.

BioMed Central - Latest articles 2010

DesT-oleoyl-CoA-DNA and DesT-palmitoyl-CoA complexes reveal that acyl chain shape directly influences the packing of hydrophobic core residues within the DesT ligand-binding domain.

Naturejobs - All Jobs Darcie J Miller 2010

Services include validating and performing ligand-binding assays for novel clinical biomarkers, immunogenicity testing, cell based assay testing and multiplex testing.

The Earth Times Online Newspaper 2010