lincRNAs

Prior to the finding, only 10 examples of the large intervention non-coding RNAs, called lincRNAs, had been found, and they were dismissed as genomic oddities rather than critical elements.

GEN News Highlights 2009

[24], [59], and a dataset of large intervening ncRNAs (1,408 "lincRNAs") identified by the H3K4me3/H3K36me3 chromatin signatures characteristic of bona fide active genes

PLoS Biology: New Articles Francesca De Santa et al. 2010

"lincRNAs" plays critical roles in both health and disease, including cancer, immune signaling and stem cell biology.

Biosingularity 2009

"The effects that these lincRNAs can have in cancer progression are much more complex than we had anticipated," said Chang.

PhysOrg.com - latest science and technology news stories 2010

The finding was the first to show that lincRNAs can affect the expression of distant genes on other chromosomes and gave an inkling of their global importance in the body.

PhysOrg.com - latest science and technology news stories 2010

Examples of extragenic Pol_II peaks in predicted enhancers overlapping annotated lincRNAs.

PLoS Biology: New Articles Francesca De Santa et al. 2010

"The effects that these lincRNAs can have in cancer progression are much more complex than we had anticipated," said Chang.

PhysOrg.com - latest science and technology news stories 2010

"There's something like 10,000 of these large intervening non-coding RNAs, or lincRNAs, in the human genome," said Chang.

PhysOrg.com - latest science and technology news stories 2010

"There's something like 10,000 of these large intervening non-coding RNAs, or lincRNAs, in the human genome," said Chang.

PhysOrg.com - latest science and technology news stories 2010

The finding was the first to show that lincRNAs can affect the expression of distant genes on other chromosomes and gave an inkling of their global importance in the body.

PhysOrg.com - latest science and technology news stories 2010