lipofuscin

Normally activated by near-starvation, SIRT-1 extends life by, among other things, reducing the amount of intracellular junk (called lipofuscin) that accumulates from metabolism.

Forbes.com: News 2009

5 Miscellaneous free-radical reactions form residues called lipofuscin or age pigment.

The New Super-Nutrition Ph.D. Richard A. Passwater 1991

5 Miscellaneous free-radical reactions form residues called lipofuscin or age pigment.

The New Super-Nutrition Ph.D. Richard A. Passwater 1991

With age, there may be insufficient digestion of damaged macromolecules and organelles by the RPE, which will lead to progressive accumulation of biological "garbage", such as lipofuscin, and release of partially digested or undigested materials.

PLoS ONE Alerts: New Articles 2009

Superoxide free radicals, which is what these garbage molecules are called, combine with fatty acids to produce lipofuscin, which is an unstable, repulsive gunk that clogs up a cell like grease clogs a drain.

La insistencia de Jürgen Fauth 2010

At the molecular level the buildup of lipofuscin is responsible for the loss of internal circulation that leads to cellular morbidity.

The Hunger Whitley Strieber 1981

She was convinced that some substance such as lipofuscin must be responsible.

The Hunger Whitley Strieber 1981

“His lipofuscin accumulation rate started an exponential rise in sample two thousand one hundred forty-one, taken at the seventy-first hour,” Charlie said.

The Hunger Whitley Strieber 1981

She was convinced that some substance such as lipofuscin must be responsible.

The Hunger Whitley Strieber 1981

“His lipofuscin accumulation rate started an exponential rise in sample two thousand one hundred forty-one, taken at the seventy-first hour,” Charlie said.

The Hunger Whitley Strieber 1981