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Examples
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• Four million Americans a year are prescribed a longacting opiod.
Doctors' Dilemma: How Real is that Pain? Melinda Beck 2011
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• Four million Americans a year are prescribed a longacting opiod.
Doctors' Dilemma: How Real is that Pain? Melinda Beck 2011
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More information: Effect of beta-2-adrenergic receptor polymorphism on response to longacting beta-2 agonist in asthma (LARGE trial): a genotype-stratified, randomised, placebo-controlled crossover trial.
PhysOrg.com - latest science and technology news stories 2009
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More information: Effect of beta-2-adrenergic receptor polymorphism on response to longacting beta-2 agonist in asthma (LARGE trial): a genotype-stratified, randomised, placebo-controlled crossover trial.
PhysOrg.com - latest science and technology news stories 2009
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The team found that lung function did not differ between groups, but participants with the genetic mutation arginine-arginine did not benefit from the addition of longacting ß2 agonist in regards to airway hyperresponsiveness.
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This may modify the risk benefit ratio of longacting beta agonists in this population.
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Individuals in a matched pair were assigned to receive inhaled longacting ß2 agonist or a placebo.
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The authors investigated whether there is a genotype-specific response to treatment with a longacting ß2 agonist in combination with an inhaled corticosteroid.
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The authors say: "IPTi with a longacting, efficacious drug such as mefloquine can reduce episodes of malaria in infants in a moderate-transmission setting.
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