from The Century Dictionary.
- noun A sterilized filtered extract of glycerin-bouillon cultures of the bacillus of glanders, containing substances from the bodies of the bacilli and their soluble products which have not been destroyed by heat.
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This consists in dropping into an eye of a suspected animal a specially prepared solution of mallein, as a result of which in an infected animal the inflammation develops in the eye, resulting in a discharge which varies in intensity from a mucopurulent character to a thick, sticky pus.
If the horse does not have glanders the mallein has no effect or, at most, it produces a slight swelling only at the point of injection.
_ -- When there is doubt as to the diagnosis, the mallein test, the inoculation test, or the complement-fixation test may be employed.
Furthermore, the injection of mallein in cases of sporotrichosis will be attended with negative results.
Much tuberculin and mallein have been furnished to State authorities for use in the agricultural colleges and experiment stations for the treatment of tuberculosis and glanders.
In several celebrated cases horses which have been affected with glanders have been known to work for years and die from other causes without ever having had the return of symptoms; but allowing that these cases may occur, they are so few and far between, and the danger of infection of glanders to other horses and to the stable attendants is so great, that no animal which has once been affected with the disease should be allowed to live unless repeated mallein tests have shown him to have become free from taint of glanders.
The mallein test is made by injecting mallein (a sterilized extract from