mechanosensation

He says the discovery of a "mechanosensation receptor" took a fair amount of brute-force work over several years by Scripps lab mates led by postdoctoral fellow

Why Does It Hurt So Bad? 2010

GLR-1 is expressed in the command interneurons, where it mediates nose-touch mechanosensation and regulates the frequency of spontaneous reversals in locomotion

PLoS ONE Alerts: New Articles 2009

Multiple TRP channel family members have been reported to be involved in mechanosensation, and altered TRPC6 channel function could influence podocyte sense for flow, stretch or pressure, thereby in turn affecting the reorganization of the podocyte actin cytoskeleton in response to physiological changes

PLoS ONE Alerts: New Articles Saskia F. Heeringa et al. 2009

Lin SY, Corey DP (2005) TRP channels in mechanosensation.

PLoS ONE Alerts: New Articles Saskia F. Heeringa et al. 2009

TRPC6 belongs to the family of transient receptor potential (TRP) channel proteins, a diverse group of voltage-independent cation-permeable channels that are expressed in many tissues including lung, kidney, brain, muscle containing tissues and blood cells where they are involved in many different signaling cascades of cell growth and mechanosensation

PLoS ONE Alerts: New Articles Saskia F. Heeringa et al. 2009

Another pathophysiological explanation for proteinuria in patients with TRPC6 mutations would be the dysfunction of mechanosensation in the slit diaphragm.

PLoS ONE Alerts: New Articles Saskia F. Heeringa et al. 2009

Schermer B, Benzing T (2007) Podocin organizes ion channel-lipid supercomplexes: implications for mechanosensation at the slit diaphragm.

PLoS ONE Alerts: New Articles Saskia F. Heeringa et al. 2009

He uses this animal to investigate aspects of nerve cell development and function, particularly with respect to touch and mechanosensation.

StAugustine.com 2009

Impaired cytoskeletal reorganization could be envisioned as a result of defective mechanosensation (e.g. through hyperactive TRPC6), which in turn leads to podocyte damage, podocyte loss and, ultimately, FSGS.

PLoS ONE Alerts: New Articles Saskia F. Heeringa et al. 2009

The height of each bar in the histogram corresponds to the overlap between the modules and functional circuits (F1) mechanosensation, (F2) egg laying, (F3) thermotaxis, (F4) chemosensation, (F5) feeding, (F6) exploration and (F7) tap withdrawal.

PLoS ONE Alerts: New Articles Raj Kumar Pan et al. 2010