Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biology The
conversion of amechanical stimulus intochemical activity .
Etymologies
from Wiktionary, Creative Commons Attribution/Share-Alike License
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Examples
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Shu Chien Science, University of California, San Diego, for pioneering work in cardiovascular physiology and bioengineering, which has had tremendous impact in the fields of microcirculation, blood rheology, and mechanotransduction in human health and disease.
Forbes.com: News Jayne Jung 2011
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Uncovering the mystery of mechanotransduction will take years, Mofrad knows, but he hopes one day the knowledge will improve human health.
PhysOrg.com - latest science and technology news stories 2010
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As mechanotransduction unfolds, an endothelial cell converts that "happy zone" of the blood's force, a mechanical signal, into a biochemical signal.
PhysOrg.com - latest science and technology news stories 2010
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Reacting to the abnormality, mechanotransduction is altered, which in turn disrupts the cells 'ability to govern a healthy physiology; and this, the researchers believe, may eventually lead to diseases such as atherosclerosis, a build-up of fatty material clogging the arteries.
PhysOrg.com - latest science and technology news stories 2010
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To better understand mechanotransduction, Mofrad studied endothelial cells, which make up the inner layer of a blood vessel.
PhysOrg.com - latest science and technology news stories 2010
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Sometimes that means a cell moves, and, in a diseased cell, focal adhesion mechanotransduction might explain how cancer spreads.
PhysOrg.com - latest science and technology news stories 2010
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(Atherosclerosis is a precursor to heart attacks, strokes, heart valve disorders and other diseases.) "Normal mechanotransduction is a good thing," Mofrad says.
PhysOrg.com - latest science and technology news stories 2010
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Earlier this year, Mofrad won a National Science Foundation CAREER award for his work on mechanotransduction, the mechanisms by which cells convert mechanical stimuli into biochemical activity.
PhysOrg.com - latest science and technology news stories 2010
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His lab established an online database so researchers can easily access and contribute information on mechanotransduction.
PhysOrg.com - latest science and technology news stories 2010
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So Mofrad's lab is working on two computer modeling projects to better understand exactly how mechanotransduction occurs at the molecular level, precisely how mechanical energy is converted to biochemical.
PhysOrg.com - latest science and technology news stories 2010
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