Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun A large bone marrow cell with a lobulate nucleus that gives rise to blood platelets.

from the GNU version of the Collaborative International Dictionary of English.

  • noun (Anat.) A large bone marrow cell not usually found in the circulating blood; it is regarded as the precursors of blood platelets; it is up to 100 μm in diameter, with a polyploid nucleus. Also referred to as megacaryocyte, megalokaryocyte, and thromboblast.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun anatomy A large cell, found in bone marrow, responsible for the production of platelets.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • noun a large bone marrow cell; regarded as the source of blood platelets

Etymologies

from Wiktionary, Creative Commons Attribution/Share-Alike License

From mega- +‎ karyocyte

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Examples

  • The cytoplasm of the megakaryocyte fragments at the edge of the cell.

    Archive 2008-02-01 James Killus 2008

  • Platelets are formed in the cytoplasm of a very large cell, the megakaryocyte.

    It's Always about the Blood James Killus 2008

  • Platelets are formed in the cytoplasm of a very large cell, the megakaryocyte.

    Archive 2008-02-01 James Killus 2008

  • The cytoplasm of the megakaryocyte fragments at the edge of the cell.

    It's Always about the Blood James Killus 2008

  • "Our study indicates that the dysregulation of PLAU in Quebec platelet disorder extends beyond megakaryocyte lineage, to involve other cells of the myeloid lineage," the investigator said.

    MedPageToday.com - medical news plus CME for physicians 2010

  • The condition also is characterized by proteolysis of platelet α-proteins such as platelet factor V and von Willebrand factor, further interfering with clot function, and with increased uPA messenger RNA levels, particularly during megakaryocyte differentiation.

    MedPageToday.com - medical news plus CME for physicians 2010

  • "Our study indicates that the dysregulation of PLAU in Quebec platelet disorder extends beyond megakaryocyte lineage, to involve other cells of the myeloid lineage," the investigator said.

    MedPageToday.com - medical news plus CME for physicians 2010

  • The condition also is characterized by proteolysis of platelet α-proteins such as platelet factor V and von Willebrand factor, further interfering with clot function, and with increased uPA messenger RNA levels, particularly during megakaryocyte differentiation.

    MedPageToday.com - medical news plus CME for physicians 2010

  • Lagrue-Lak-Hal AH, Debili N, Kingbury G, Lecut C, Le Couedic JP, et al. (2001) Expression and function of the collagen receptor GPVI during megakaryocyte maturation.

    PLoS ONE Alerts: New Articles 2009

  • Boer AK, Los EL, Esselink MT, Vellenga E (2005) Stem cell factor synergistically enhances thrombopoietin-induced STAT5 signaling in megakaryocyte progenitors through JAK2 and Src kinase.

    PLoS ONE Alerts: New Articles Lina Han et al. 2009

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