Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- adjective Of or pertaining to the mesocortex.
Etymologies
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Examples
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ITI-007 also exhibits mesocortical and mesolimbic selectivity as evidenced by regionally selective increases in dopamine release and phosphorylation of glutamatergic NMDA NR2B receptors in response to dopamine D1 receptor activation.
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Given the unique pharmacological profile of ITI-007 that includes potent 5-HT2A receptor antagonism, pre-synaptic partial agonism and post-synaptic antagonism of D2 receptors, and functional mesolimbic/mesocortical selectivity of dopaminergic and glutamatergic interactions,
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