Definitions
Sorry, no definitions found. Check out and contribute to the discussion of this word!
Etymologies
Sorry, no etymologies found.
Support
Help support Wordnik (and make this page ad-free) by adopting the word minimal change disease.
Examples
Sorry, no example sentences found.
vendingmachine commented on the word minimal change disease
The cause of minimal change disease is not fully known but it is believed to be an immune disorder in which T cells release a cytokine that damages the epithelial foot processes of the glomeruli. This leads to a leakage of albumin by the kidney. Certain events such as a viral infection, an allergic reaction, a bee sting, or an immunization may trigger an attack of MCD.
Minimal change disease is the most common form of the nephrotic syndrome in children aged 2 to 12 years. It is the cause of nephrotic syndrome in about 90% of children younger than 10 years, about 50% to 70% of older children, and 10% to 15% of adults.
March 23, 2016