neoantigen

What we’ve shown so far is that these large complex chromosomal rearrangements are frequent in mesothelioma and may provide a source of neoantigens (cancer proteins) that the immune system can recognize,” says Aaron Mansfield, M.D., a Mayo Clinic oncology researcher and lead author on the paper.

Science Saturday: Discovery advances potential individualized treatment for mesothelioma Dana Sparks 2018

These abnormal proteins can generate peptides called neoantigens that are recognized as non-self by the immune system, prompting an immune response that targets cancer cells for destruction.

Peptides from abnormal RNA processing in cancer offer an immunotherapy target Al Charest 2025

These abnormal proteins can generate peptides called neoantigens that are recognized as non-self by the immune system, prompting an immune response that targets cancer cells for destruction.

Peptides from abnormal RNA processing in cancer offer an immunotherapy target Al Charest 2025