Definitions
from The American Heritage® Dictionary of the English Language, 5th Edition.
- noun The failure of paired chromosomes or sister chromatids to separate and go to different cells during meiosis.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun genetics The failure of
chromosome pairs to separate properly duringmeiosis
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- noun meiosis in which there is a failure of paired homologous chromosomes to separate; results in an abnormal number of chromosomes in the daughter cells
Etymologies
from Wiktionary, Creative Commons Attribution/Share-Alike License
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Examples
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When nondisjunction occurs, the resulting eggs may carry too few or too many chromosomes, a state called aneuploidy.
Delayed Childbearing 1995
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Embryos that are trisomic contain, instead of matched pairs of chromosomes, one too many of a given chromosome, most commonly chromosome 13, 18, 21 (which is responsible for Down syndrome), X, or Y. Trisomies are the result of a glitch known as nondisjunction, which occurs principally during the creation of egg cells (although sperm cells may also exhibit such errors).
Delayed Childbearing 1995
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Embryos that are trisomic contain, instead of matched pairs of chromosomes, one too many of a given chromosome, most commonly chromosome 13, 18, 21 (which is responsible for Down syndrome), X, or Y. Trisomies are the result of a glitch known as nondisjunction, which occurs principally during the creation of egg cells (although sperm cells may also exhibit such errors).
Delayed Childbearing 1995
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When nondisjunction occurs, the resulting eggs may carry too few or too many chromosomes, a state called aneuploidy.
Delayed Childbearing 1995
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Shi Q, King RW (2005) Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines.
PLoS ONE Alerts: New Articles Vincent Gache et al. 2010
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Feingold E, Savage A, Avramopoulos D, Freeman S, et al. (1997) Characterization of susceptible chiasma configurations that increase the risk for maternal nondisjunction of chromosome 21.
PLoS ONE Alerts: New Articles Vincent Gache et al. 2010
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This makes sense, since these cancers often fail to inactivate the X chromosome, and X chromosome nondisjunction leads to more male worms.
Ars Technica Ars Staff 2010
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Most of what goes wrong during meiosis-to-fertilization-to-mitosis results in chromosomal abnormalities, usually nondisjunction, thus providing a mechanism for aneuplodiy -- rather than an insistence that it really does happen.
WN.com - Articles related to Plants give up some deep secrets of drought resistance 2010
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Koehler KE, Hawley RS, Sherman S, Hassold T (1996) Recombination and nondisjunction in humans and flies.
PLoS ONE Alerts: New Articles David Obeso et al. 2010
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Koehler KE, Hawley RS, Sherman S, Hassold T (1996) Recombination and nondisjunction in humans and flies.
PLoS ONE Alerts: New Articles David Obeso et al. 2010
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