Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun Any of a family of
porins that facilitatestransport throughnuclear pores in the nuclearenvelope of cells
Etymologies
from Wiktionary, Creative Commons Attribution/Share-Alike License
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Examples
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Additionally, reduction in expression of nucleoporin 153 by siRNA targeting reduced ERK1/2 nuclear activity in cancer cells.
Elites TV PLoS ONE 2010
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Since nuclear pore complexes are part of the nuclear membrane, which delineates the cell nucleus, it had been assumed that when a gene was regulated by a nucleoporin, it somehow had to make its way to the periphery of the nucleus, adjacent to the nuclear pore.
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For more than a decade, however, scientists had known that when the protein called Nup98, a nucleoporin, abnormally fuses with certain proteins that regulate gene expression, the marriage causes leukemia.
PhysOrg.com - latest science and technology news stories 2010
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± 0.00E+00 0.92 1.08 - XP_133073. 3 PREDICTED: nucleoporin 205 isoform 1 133 3 2 246 6 4 2.01E-05
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NP_035693. 2 peroxiredoxin 2 FUS nucleoporin pigpen1 119 246 2 6 3 4 149 2.01E-052 ± 5.68E-063 2.03E-05
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FUS NP_631888. 1 pigpen NP_035693. 2 peroxiredoxin 2 NP_444304. 1 nucleoporin 62
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