Definitions
from The American Heritage® Dictionary of the English Language, 5th Edition.
- noun Either of two neuropeptide hormones synthesized in the hypothalamus that regulate sleep and wakefulness and whose dysfunction causes narcolepsy.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biochemistry Either of two
neuropeptide hormones found invertebrates ; thehypocretins
Etymologies
from The American Heritage® Dictionary of the English Language, 4th Edition
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Examples
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Suvorexant, formerly code-named MK-4305, is known as an orexin receptor antagonist.
Merck to File Insomnia Drug Application Peter Loftus 2012
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Giving mice a shot of a hormone called orexin, which promotes wakefulness, also caused amyloid-beta levels to increase.
Signs of the Times 2009
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Almorexant is a new kind of drug, one that temporarily reduces levels of the brain chemical orexin, which is thought to help keep people awake.
Glaxo Gives Actelion 2008
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The researchers focused on a protein known as orexin-A, which is activated in the brain by physical activity, moods and thoughts.
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That message is delivered via neurons in the brain's hypothalamus containing the chemical known as orexin and the sympathetic nervous system, the studies in mice and rats suggest.
PhysOrg.com - latest science and technology news stories 2009
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This chemical, called orexin by some scientists and hypocretin by others, is produced by a small pocket of neurons in the hypothalamus.
Science News / Features, Blog Entries, Column Entries, Issues, News Items and Book Reviews 2009
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That message is delivered via neurons in the brain's hypothalamus containing the chemical known as orexin and the sympathetic nervous system, the studies in mice and rats suggest.
PhysOrg.com - latest science and technology news stories 2009
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That message is delivered via neurons in the brain's hypothalamus containing the chemical known as orexin and the sympathetic nervous system, the studies in mice and rats suggest.
PhysOrg.com - latest science and technology news stories 2009
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Suvorexant is designed to block the effect of orexin in the brain, promoting sleep in insomniacs.
Merck to File Insomnia Drug Application Peter Loftus 2012
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Last year, GlaxoSmithKline PLC and Actelion Ltd. dropped development of another orexin receptor antagonist, almorexant, amid questions about that compound's safety and tolerability.
Merck to File Insomnia Drug Application Peter Loftus 2012
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