Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun A
glycopeptide antibiotic being developed for the treatment of serious Gram-positiveinfections .
Etymologies
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Examples
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The FDA posted a review Monday of telavancin and oritavancin ahead of the meeting.
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Later Wednesday the same panel will consider Targanta Therapeutics Corp. 's oritavancin and will look at iclaprim by Swiss biotech company Arpida Ltd. Thursday.
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On Wednesday the panel is expected to vote on Theravance Inc. 's telavancin and Targanta Therapeutics Corp. 's oritavancin before considering iclaprim by Swiss biotech company Arpida Ltd. Thursday.
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The agency said one of the studies showed that a lower percentage of oritavancin patients were considered a treatment success for MRSA, and it will ask the panel to comment on that finding.
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In a review of Targanta's oritavancin, the FDA looked at the impact of the drug on 11 types of bacteria -- including MRSA -- compared with vancomycin's effects.
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Overall, the agency said both telavancin and oritavancin met study goals of being at least as good as a vancomycin -- an older, generic antibiotic -- at treating skin infections.
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Targanta's oritavancin has had a troubled history.
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New drugs are coming for complicated skin infections: daptomycin, oritavancin: antibiotics battle gram-positive pathogens.
OpEdNews - Quicklink: A new compound fights drug-resistant bacteria 2008
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The research was conducted by Targanta Therapeutics Corp., a Cambridge, Mass., company that has applied to sell the antibiotic, oritavancin, in the U.S.
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Targanta, in briefing documents posted on FDA's Web site, said oritavancin was "safe and well-tolerated."
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