Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun A homologous gene that is related to those in different organisms by descent from the DNA of a common ancestor and that may or may not have the same function.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun genetics either of two or more homologous gene sequences found in different species related by linear descent

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[Back-formation from orthologous : ortho– + (homo)logous.]

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Examples

  • Even if it takes longer to complete the human interactome it would be much more informative to have of map of the ortholog proteins in a sufficiently close species to compare with like mouse.

    Public Rambling Pedro Beltrao 2006

  • As before I created groups of H. sapiens proteins with different average age using the reciprocal best blast hit method to determine the most likely ortholog in eleven other eukaryotic species see figure 1 for species names.

    Public Rambling Pedro Beltrao 2006

  • Even if it takes longer to complete the human interactome it would be much more informative to have of map of the ortholog proteins in a sufficiently close species to compare with like mouse.

    Archive 2006-04-01 Pedro Beltrao 2006

  • Zac at ortholog.com writes about an experimental test of buying irrationality using Ebay.

    Mind Hacks: February 2006 Archives 2006

  • In order to create groups of S. cerevisiae proteins with different average age I used the reciprocal best blast hit method to determine the most likely ortholog in eleven other yeast species see figure 1 for species names.

    Public Rambling Pedro Beltrao 2006

  • As before I created groups of H. sapiens proteins with different average age using the reciprocal best blast hit method to determine the most likely ortholog in eleven other eukaryotic species see figure 1 for species names.

    Archive 2006-07-01 Pedro Beltrao 2006

  • In order to create groups of S. cerevisiae proteins with different average age I used the reciprocal best blast hit method to determine the most likely ortholog in eleven other yeast species see figure 1 for species names.

    Archive 2006-07-01 Pedro Beltrao 2006

  • Zac at ortholog.com writes about an experimental test of buying irrationality using Ebay.

    Mind Hacks: the price is right regardless of the cost 2006

  • Chickens have ovocleidin, but geese have an ortholog, ansocalcin, and ostriches have struthiocleidin.

    ScienceBlogs Channel : Life Science 2010

  • Drosophila ortholog of mammalian "Heterochromatin Protein 1", to target genes for dSETDB1.

    Elites TV 2010

  • The term "ortholog" was coined in 1970 by the molecular evolutionist Walter Fitch.[5]

    Sequence homology Contributors to Wikimedia projects 2022

  • Orthologs, or orthologous genes, are genes in different species that originated by vertical descent from a single gene of the last common ancestor.

    Sequence homology Contributors to Wikimedia projects 2022

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