Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun A calcium-binding substance produced by osteoblasts that is essential to bone mineralization and can be used as a biomarker for osteoporosis. It may also act as a hormone to increase insulin production and insulin sensitivity.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biology A protein found in bone and dentin, manufactured by osteoblasts. It plays a role in mineralization and calcium ion homeostasis.

Etymologies

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Examples

  • Early this year, Dr. Karsenty's team published a study demonstrating that in mice a protein called osteocalcin, which is produced by bone-forming cells called osteoblasts, binds to a specific receptor on cells of the testes.

    NYT > Home Page By AMANDA SCHAFFER 2011

  • Early this year, Dr. Karsenty's team published a study demonstrating that in mice a protein called osteocalcin, which is produced by bone-forming cells called osteoblasts, binds to a specific receptor on cells of the testes.

    NYT > Home Page By AMANDA SCHAFFER 2011

  • The first clue that the skeleton may have an important role in regulating blood glucose came in 2007 when Dr. Karsenty discovered that a hormone released by bone - known as osteocalcin - can regulate glucose levels.

    EurekAlert! - Breaking News 2010

  • The first clue that the skeleton may have an important role in regulating blood glucose came in 2007 when Dr. Karsenty discovered that a hormone released by bone - known as osteocalcin - can regulate glucose levels.

    Newswise: Latest News 2010

  • For our bones to be optimally healthy, one of the proteins found in bone-a protein called osteocalcin-needs to be chemically altered through the process of carboxylation.

    The World's Healthiest Foods 2010

  • The first clue that the skeleton may have an important role in regulating blood glucose came in 2007 when Dr. Karsenty discovered that a hormone released by bone - known as osteocalcin - can regulate glucose levels.

    PhysOrg.com - latest science and technology news stories 2010

  • For our bones to be optimally healthy, one of the proteins found in bone-a protein called osteocalcin-needs to be chemically altered through the process of carboxylation.

    The World's Healthiest Foods 2010

  • The mechanics of vitamin K2 are that it activates a bone protein called osteocalcin, which binds calcium in the bones, thus preventing calcium from moving into the bloodstream and being deposited in the arteries, with often fatal consequences.

    unknown title 2009

  • For our bones to be optimally healthy, one of the proteins found in bone-a protein called osteocalcin-needs to be chemically altered through the process of carboxylation.

    The World's Healthiest Foods 2009

  • Vitamin K, abundant in these plants, plays a role in building the bone protein osteocalcin and binding calcium to the bone matrix.

    Carrie Wiatt, M.S.: Keep Your Bones Strong After Menopause M.S. Carrie Wiatt 2011

  • Karsenty had become interested in osteocalcin, one of the most abundant proteins in bone.

    Does the key to anti-ageing lie in our bones? David Cox 2021

  • Osteocalcin, a hormone produced in the bones, could one day provide treatments for age-related issues such as muscle and memory loss

    Does the key to anti-ageing lie in our bones? David Cox 2021

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