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overexpression

Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun genetics The artificial expression of a gene in increased quantity

Etymologies

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Examples

  • The challenge was to measure the quantity of overexpression, that is, how much excess protein was being produced by each of the three variants.

    Health News from Medical News Today 2009

  • So called 'overexpression' can occur when spliced genes that synthesize such chemicals become hyperactive inside the plant and result in potentially toxic plant tissues, lethal not just to meal worms and other crop pests, but to cats, dogs, birds, butterflies and other wildlife; and to their creators.

    What do Bill Gates, the Rockefellers, and Oggie Dog have in common? 2008

  • Various news outlets are reporting that researchers from the UK and Israel claim that even a quick bout of light in the middle of the night can trigger an 'overexpression' of brain cells linked to cancer.

    Lead Stories from AOL 2010

  • The overproduction, or 'overexpression', of the epidermal growth factor receptor (EGFR) is one of th ...

    THE MEDICAL NEWS 2009

  • Effect of interleukin-10 overexpression on the properties of healing tendon in a murine patellar tendon model.

    CHOP scarless fetal wound healing publications 2010

  • Scientists believe the overgrowth associated with Beckwith Wiedemann Syndrome and hemihypertrophy may develop because of improper inactivation of one or more growth-suppressing genes, or because of overexpression of genes that encourage cell growth.

    Beckwith-Weidemann Syndrome 2009

  • Cystic adenomatoid malformations are induced by localized FGF10 overexpression in fetal rat lung.

    Congenital cystic adenomatoid malformation publications 2010

  • Zhang EY, Stein R, Chang S, Zheng Y, Zderic SA, Wein AJ, Chacko S: Smooth muscle hypertrophy following partial bladder outlet obstruction is associated with overexpression of non-muscle caldesmon.

    Publications of the Urology Division 2010

  • Typically, proto-oncogenes are normal cellular genes that, when activated by mutation or overexpression, promote cancer.

    The Emperor of All Maladies Siddhartha Mukherjee 2010

  • Activation or overexpression of a proto-oncogene see below promotes the transformation of a cell from normal to a cancer cell.

    The Emperor of All Maladies Siddhartha Mukherjee 2010

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