Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • adjective Of or relating to the release of locally acting substances from endocrine cells.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • adjective Describing a hormone or other secretion released from endocrine cells into the surrounding tissue rather than into the bloodstream

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[German parakrin : Greek para-, para- + Greek krīnein, to separate; see krei- in Indo-European roots.]

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Examples

  • But it has not been possible to detect chemical messages that travel between cells that are nearby but not in contact - called paracrine signals - because they are highly localized and they are produced in concentrations that have been below detection levels.

    EurekAlert! - Breaking News 2008

  • As such, these cells have the potential to move the regenerative medical field beyond the classic paracrine mechanisms neoangiogenesis and down-regulation of inflammation toward tissue and bone repair and regeneration.

    unknown title 2011

  • Mohr S, Grant MB (2008) Hyperglycemia-induced reactive oxygen species toxicity to endothelial cells is dependent on paracrine mediators.

    PLoS ONE Alerts: New Articles Franco Folli et al. 2010

  • Having clearly understood the regulatory nature of DOSHAS, I should be able to see how DOSHAVAISHAAYA should be appreciated as a disturbance of homeostatic neural, neurocrine, endocrine, paracrine, autocrine regulatory mechanisms.

    Recently Uploaded Slideshows supri1278 2010

  • "Increased apelin levels may act as a paracrine mediator produced from BMMCs and may play an important role in the treatment of heart failure through autocrine and paracrine mechanisms," Dr. Gao concluded.

    PhysOrg.com - latest science and technology news stories 2010

  • The researchers propose that Sfrp5 neutralizes noncanonical JNK activation by Wnt5a in macrophages and adipocytes via paracrine and autocrine mechanisms, respectively.

    PhysOrg.com - latest science and technology news stories 2010

  • It explains the precise and moment to moment effects of autocrine, paracrine and endocrine secretions.

    Recently Uploaded Slideshows supri1278 2010

  • Zingman LV, Hodgson DM, Rauzier JM, Kane GC, et al. (2002) Stem cell differentiation requires a paracrine pathway in the heart.

    PLoS ONE Alerts: New Articles Kemar Brown et al. 2010

  • They also noted that adipose tissue itself is a source for a number of paracrine factors that might affect retinal ganglion cells.

    MedPageToday.com - medical news plus CME for physicians 2010

  • Chakraborty G, Jain S, Kundu GC (2008) Osteopontin promotes vascular endothelial growth factor-dependent breast tumor growth and angiogenesis via autocrine and paracrine mechanisms.

    PLoS ONE Alerts: New Articles Donald Courter et al. 2010

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