Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A signal transduction adaptor protein

Etymologies

Sorry, no etymologies found.

Examples

  • Rajfur Z, Borchers C, Schaller MD, Jacobson K (2003) JNK phosphorylates paxillin and regulates cell migration.

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  • Subculture on collagen type I was associated with changed expression of several proteins, including a significant upregulation of the paxillin-like LIM protein, hydrogen-peroxide-induced clone 5 (Hic-5), and increased the susceptibility of the cells to apoptosis in response to physiological triggers.

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  • Src usually works with FAK to phosphorylate tyrosines in proteins like paxillin, which then disassemble the focal adhesion.

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  • Donais K, Whitmore LA, Thomas SM, Turner CE, et al. (2004) FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly.

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  • Nickel C, Thomas S, Cantley LG (2002) Hepatocyte growth factor induces ERK-dependent paxillin phosphorylation and regulates paxillin-focal adhesion kinase association.

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