peptidase

CD26/dipeptidyl peptidase IV: A regulator of immune function and a potential molecular target for therapy.

The UltraMind Solution M.D. Mark Hyman 2009

University, who worked at that time on translocation of proteins across the endoplasmic reticulum (ER) membrane, a process that involves cleavage of the leader peptide by signal peptidase, to Jeffrey Roberts in Cornell University who worked on E. coli RecA protein-directed cleavage of phage l repressor and its requirement for polynucleotide, and to Harvey Lodish at the M.I.T. who worked, among other subjects, on processing of viral polyproteins.

Aaron Ciechanover - Autobiography 2005

It was not until the mid-1990s that researchers saw another way: An enzyme called dipeptidyl peptidase four DPP4 broke down GLP, and by inhibiting it, researchers could boost GLP levels in the body.

Merck Starts Diabetes Race 2006

Those results, as well as data on a class of drugs known as dipeptidyl peptidase IV inhibitors DPIV, could provide a catalyst for OSI shares, the Wachovia analyst said.

OSI's Macugen Still Burdened By Lucentis Threat 2006

Osborne, who expects FDA approval of Novartis' Galvus in the first quarter, is one of a handful of analysts who believe Byetta will see significant competition from a new class of diabetes treatments known as dipeptidyl peptidase inhibitors.

Amylin Gets Euro OK For Byetta, Shares Fall 2006

Both pills work by inhibiting an enzyme called dipeptidyl peptidase 4 DPP-IV, which breaks down hormones that help control blood sugar.

Merck, Novartis Square Off In Diabetes DuelDiabetes Duel 2006

Recent comments by Dr. Daniel Drucker, a professor at the University of Toronto and leader in diabetes and endocrinology, suggested dipeptidyl peptidase agents such as those being developed by Merck and Novartis have potential as effective second-line treatments for type 2 diabetes, according to Morgan Stanley.

Merck's Januvia Has 'Huge' Commercial Potential For Diabetes 2006

Some of the preexisting protein translocation apparatus of the endosymbiont appears to have been commandeered, including molecular chaperones, the signal peptidase, and some components of the protein-targeting machinery.

3 recent reports use evolution to study mechanisms of antibody diversification - The Panda's Thumb 2006

A peptidase enzyme capable of acting on any peptide linkage in a peptide chain.

Alcohol and The Addictive Brain Kenneth Blum 1991

A peptidase enzyme capable of acting on any peptide linkage in a peptide chain.

Alcohol and The Addictive Brain Kenneth Blum 1991