Definitions
from The American Heritage® Dictionary of the English Language, 5th Edition.
- noun A crystalline alkaloid, C15H21N3O2, extracted from the Calabar bean, used in the form of its sulfate as a miotic and in the form of its salicylate as a cholinergic agent.
from The Century Dictionary.
- noun An alkaloid constituting the active principle of the Calabar bean.
- noun It is a powerful depressant and nerve-poison: used to counteract strychnine and atropin, also to contract the pupil. Its formula is C15H21O2N3. Also called
eserine .
from the GNU version of the Collaborative International Dictionary of English.
- noun (Chem.) An alkaloid found in the Calabar bean (the seed of
Physostigma venenosum ), and extracted as a white, tasteless, substance, amorphous or crystalline; -- formerly calledeserine , with which it was regarded as identical.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun chemistry A
parasympathomimetic , areversible cholinesterase inhibitor alkaloid of theCalabar bean , used to treat certainmedical conditions.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- noun used in treatment of Alzheimer's disease and glaucoma
Etymologies
from The American Heritage® Dictionary of the English Language, 4th Edition
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Examples
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He would see what happens to vervet monkeys every single month at Aberdeen Proving Ground in Maryland: in a crude simulation of a nerve agent attack, the monkeys are given a massive overdose of a drug called physostigmine.
Kathy Guillermo: How Not to Save Lives Kathy Guillermo 2011
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In one form of chemical casualty management training, anesthetized primates are given a chemical called physostigmine, which simulates exposure to a nerve gas by causing cholinergic intoxication.
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In one form of chemical casualty management training, anesthetized primates are given a chemical called physostigmine, which simulates exposure to a nerve gas by causing cholinergic intoxication.
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The reversal of anticholinergic drug-induced delirium and coma with physostigmine.
The Neuropsychiatric Guide to Modern Everyday Psychiatry Michael Alan Taylor 1993
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Primary treatment is physostigmine, which readily crosses the blood-brain barrier and counters peripheral and central cholinergic blockade.
The Neuropsychiatric Guide to Modern Everyday Psychiatry Michael Alan Taylor 1993
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One report 252 states that IV physostigmine can do the same on a transient basis, but that finding cannot be applied to clinical practice at this time.
The Neuropsychiatric Guide to Modern Everyday Psychiatry Michael Alan Taylor 1993
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When an antidote such as physostigmine for anticholinergic toxicity to drug toxicity is not available, as is often the case, the clinician may need to wait several days or weeks for the condition to clear fully.
The Neuropsychiatric Guide to Modern Everyday Psychiatry Michael Alan Taylor 1993
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It responds to the central cholinesterase inhibitor, physostigmine (2 mg IV); the dosage may be repeated in 20 minutes and again in 30 minutes (145).
The Neuropsychiatric Guide to Modern Everyday Psychiatry Michael Alan Taylor 1993
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Anticholinergic delirium was diagnosed, all psychotropic medication was discontinued, subcutaneous physostigmine was administered, and she became essentially symptom-free within 48 hours.
The Neuropsychiatric Guide to Modern Everyday Psychiatry Michael Alan Taylor 1993
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Tricyclic antidepressant poisoning: Reversal of coma, choreoathetosis, and myoclonus by physostigmine.
The Neuropsychiatric Guide to Modern Everyday Psychiatry Michael Alan Taylor 1993
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