Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biochemistry A
protein found inplatelets
Etymologies
from Wiktionary, Creative Commons Attribution/Share-Alike License
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Examples
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Interaction between the newly generated 3-phosphorylated phosphoinositides and distinct structural motifs, such as pleckstrin homology (PH) domain, can regulate the activity of different proteins through their membrane targeting or direct modulation of their enzymatic activity
PLoS ONE Alerts: New Articles Tania Maffucci et al. 2009
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Sec3-N adopts a pleckstrin homology (PH) fold, despite having no detectable sequence homology with other PH domains of known structure.
Naturejobs - All Jobs Masami Yamashita 2010
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Phlda2 (pleckstrin homology-like domain, family A, member 2) was identified in C2
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These lipids bind to the pleckstrin homology (PH) domains of proteins such as PKB (Akt) and control the activity and subcellular localisation of a diverse array of signal transduction molecules
PLoS ONE Alerts: New Articles Veronica Ulici et al. 2010
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Morozov P, Frank D, Musalo R, Lemmon MA, et al. (2002) Phosphoinositide binding by the pleckstrin homology domains of Ipl and Tih1.
PLoS ONE Alerts: New Articles Veronica Ulici et al. 2010
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Morozov P, Frank D, Musalo R, Lemmon MA, et al. (2002) Phosphoinositide binding by the pleckstrin homology domains of Ipl and Tih1.
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Phlda2 (pleckstrin homology-like domain, family A, member 2) was identified in C2
PLoS ONE Alerts: New Articles Veronica Ulici et al. 2010
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These lipids bind to the pleckstrin homology (PH) domains of proteins such as PKB (Akt) and control the activity and subcellular localisation of a diverse array of signal transduction molecules
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PDGF, platelet-derived growth factor; PDK1, 3-phosphoinositide-dependent protein kinase-1; PH, pleckstrin homology; PH-in, protein kinase B in an inactive conformation; PKB, protein kinase B Author Summary
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Milburn CC, Deak M, Kelly SM, Price NC, Alessi DR, et al. (2003) Binding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational change.
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