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  • noun biochemistry A very large protein that maintains the structural integrity of tissue


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  • When the two plectin CH domains can separate, the affinity for F-actin is approximately three times greater than when the two CH domains are cross-linked (the disulfide cross-link is indicated by the space filling atoms at the CH1-CH2 interface) in a closed conformation Affiliations

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  • Additionally, we found a number of proteins known to interact with both actin and microtubules, such as MACF1 and plectin, pointing to a strong link between these two types of filaments in egg extract system.

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  • - actinin's ABD to F-actin is likely to explain observations made about plectin

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