Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biochemistry A
protein (or one of a larger group) whose function is to modifygene expression via changes tochromatin
Etymologies
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Examples
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Through a series of experiments, the team worked backward from this observation to show that a group of proteins called the polycomb repressive complex 1 (PRC1) that silences genes must first bind to a particular methylated address on a histone and,
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A group of proteins called the polycomb repressive complex 1 (PRC1) that silences genes must first bind to a particular methylated address on a histone and,
innovations-report 2010
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Through a series of experiments, the team worked backward from this observation to show that a group of proteins called the polycomb repressive complex 1 (PRC1) that silences genes must first bind to a particular methylated address on a histone and,
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A group of proteins called the polycomb repressive complex 1 (PRC1) that silences genes must first bind to a particular methylated address on a histone and,
innovations-report 2010
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The mechanism by which 'polycomb' proteins critical for embyronic stem cell function and fate are targeted to DNA has been identified by UCL scientists.
PhysOrg.com - latest science and technology news stories 2010
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Discovering that polycomb also binds to these RNAs shows how polycomb might be recruited to genes, which are then repressed to maintain the identities of different cell types.
PhysOrg.com - latest science and technology news stories 2010
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However, although polycomb proteins repress genes, they are actually in
PhysOrg.com - latest science and technology news stories 2010
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PRC2 (polycomb repressive complex-2) is present in all multicellular organisms and has been shown to be important in stem cell differentiation and early embryonic development.
PhysOrg.com - latest science and technology news stories 2010
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Furthermore, profiling data of genes coding for chromatin regulators of homeobox genes, including components of polycomb repressor complex 2 (PRC2), indicated lacking expression of EZH2 in LOUCY and exclusive expression of
BioMed Central - Latest articles Stefan Nagel 2010
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Moreover, targets of the polycomb repressor complex in breast cancer and embryonic stem cells were more methylated in luminal B tumours than in other tumours.
BioMed Central - Latest articles Karolina Holm 2010
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