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- noun Plural form of
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The two polyproteins could generate two different combinations of peptides in different neurons, suggesting a way to produce physiological or behavioral programs with partially overlapping components.
While studying a neuropeptide gene expressed in neuron number R15, I discovered that the gene was also expressed in some other neurons, but that its primary transcript was alternatively spliced in different neurons to give different polyproteins.
University, who worked at that time on translocation of proteins across the endoplasmic reticulum (ER) membrane, a process that involves cleavage of the leader peptide by signal peptidase, to Jeffrey Roberts in Cornell University who worked on E. coli RecA protein-directed cleavage of phage l repressor and its requirement for polynucleotide, and to Harvey Lodish at the M.I.T. who worked, among other subjects, on processing of viral polyproteins.
Protease (PR) inhibitors (PIs) prevent the maturation of infectious particles by blocking cleavage of gag-pol polyproteins by the viral protease
An alignment was created for the polyproteins of each genotype.