Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun Plural form of
polysome .
Etymologies
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Examples
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In summary, our data indicate that ZNF9 associates with translating polysomes and that the strength and mode of the interaction is consistent with those of other translation factors ZNF9 Activates Cap-Independent Translation of the Human ODC mRNA
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To determine if ZNF9 copurifies with human polysomes, lysates from HeLa cells were loaded onto a sucrose cushion and the polyribosome fraction was isolated.
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ZNF9 would be released from the polysomes with intermediate concentrations of salt.
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Cardinali B (2003) La protein is associated with terminal oligopyrimidine mrnas in actively translating polysomes.
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Waterman M (2008) Ires-Mediated pathways to polysomes: nuclear versus cytoplasmic routes.
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In summary, our experiments indicate that ZNF9 associates with actively translating polysomes and activates cap-independent translation of ODC in cultured cell lines.
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VSG221 RNAi (Fig. 5C), most of the ribosomes were associated with polysomes.
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Analysis of polysomes in the stalled cells showed that the translation arrest is mediated at the level of translation initiation rather than elongation.
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Polysome analysis showed a drastic decrease in polysomes in the arrested cells.
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This translation arrest was correlated with disassociation of ribosomes from the endoplasmic reticulum (ER) and a drastic reduction in polysomes, arguing that the translation arrest was operating at the level of translation initiation.
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