from The American Heritage® Dictionary of the English Language, 5th Edition.

  • adjective Of or involving two or more synapses in the nervous system.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • adjective of a reflex or impulse of or involving multiple synapses


Sorry, no etymologies found.


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  • Carbamazepine has been demonstrated to decrease seizure activity in animals with electrically and chemically induced seizures. 5 It is believed to act by, "reducing polysynaptic responses and blocking the post-tetanic potentiation."


  • Bottom, with a hyperpolarizing bias current to prevent PIC activation, the same stimulation only evoked a polysynaptic EPSP (lower plot).

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  • Centrally acting Alpha 2 - noradrenergic agonist acting primarily to decrease polysynaptic reflex activity

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