post-transcriptional

Areas of laboratory research interest include immune cell (T -, B -, NK-cell) signal transduction and cytoskeletal dynamics, dendritic cells and immune tolerance infectious causes of autoimmune disease and CD40-ligand transcriptional and post-transcriptional regulation in SLE.

Pediatric Rheumatology Fellowship 2010

An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells.

Advanced Information: The 2006 Nobel Prize in Physiology or Medicine 2006

The paper in PNAS suggests that the actual positioning of the motifs is associated with small RNA molecules that are involved with a process called post-transcriptional gene silencing PTGS.

IBM Discovery Could Shed New Light on Workings of the Human Genome - The Panda's Thumb 2006

The gene is spliced together out of portions called exons, excluding the introns, a bit of post-transcriptional editing that permits splice variants to be made, and that can increase the diversity of gene products.

We are as worms - The Panda's Thumb 2005

The gene is spliced together out of portions called exons, excluding the introns, a bit of post-transcriptional editing that permits splice variants to be made, and that can increase the diversity of gene products.

The Panda's Thumb: November 2005 Archives 2005

Since the same peptides may undergo post-transcriptional or post-translational modification, the submerged areas of the NGF iceberg loom very large.

Nobel Lecture The Nerve Growth Factor: Thirty-Five Years Later 1986

Although this model is largely descriptive and hypothetical, it provides a necessary framework to design experiments to test the exact role of minimal introns in post-transcriptional regulation.

PLoS ONE Alerts: New Articles Jiang Zhu et al. 2010

HIF-1 activity depends on the inhibition of the post-transcriptional hydroxylation of the subunit α by prolyl hydroxylases

PLoS ONE Alerts: New Articles Daniela Trisciuoglio et al. 2010

The regulation of NADP+-GDH activity was not reflected at the level of gene transcription thereby implicating post-transcriptional modification as a regulatory mechanism in response to nitrogen availability.

BioMed Central - Latest articles Catriona Harper 2010

Although the results presented in this study are largely descriptive and correlative and the model are hypothetical, these observations provided a necessary framework to design experiments to test the exact role of minimal introns in post-transcriptional regulation.

PLoS ONE Alerts: New Articles Jiang Zhu et al. 2010