pre-clinical

Due to the uncertainty, upfront payments for these so-called pre-clinical deals average about $15 million, compared with almost $40 million for a drug in phase II development, according to Elsevier's Strategic Transactions Database.

Abbott Labs Licenses Molecules from Reata Jonathan D. Rockoff 2011

The previous biggest upfront payment for pre-clinical compounds, Elsevier says, was the $130 million that Celgene Corp. paid upfront to Agios Pharmaceuticals Inc. last year 2010 for cancer drug candidates.

Abbott Labs Licenses Molecules from Reata Jonathan D. Rockoff 2011

Researchers in a pre-clinical study at Northwestern University have developed a brand new approach to food allergy treatment.

Susan Weissman: New and Promising Food Allergy Treatment 'Tricks' the Immune System Susan Weissman 2011

Researchers in a pre-clinical study at Northwestern University have developed a brand new approach to food allergy treatment.

Susan Weissman: New and Promising Food Allergy Treatment 'Tricks' the Immune System Susan Weissman 2011

They were once used for toxicology and pre-clinical drug testing by the Coulston Foundation until the late 1990s.

Coalition to petition NIH to return research chimps to New Mexico 2011

While the pre-clinical data and preliminary results in select patients, often look promising, confirming these findings in subsequent larger long-term studies apparently proves challenging.

Dr. Sharma’s Obesity Notes » Blog Archive » Maestro Vagal Stimulation Device Fails to Measure Up? 2009

"To our knowledge, this is the first study to identify a risk of increased falls related to a diagnosis of pre-clinical Alzheimer's disease," says Susan Stark, an assistant professor of occupational therapy and neurology at Washington University in St. Louis.

Falls linked to early Alzheimer's disease 2011

Elsevier projects there will be roughly 100 link-ups this year between big firms and small biotechs over the pre-clinical assets.

Abbott Labs Licenses Molecules from Reata Jonathan D. Rockoff 2011

"To our knowledge, this is the first study to identify a risk of increased falls related to a diagnosis of pre-clinical Alzheimer's disease," says Susan Stark, an assistant professor of occupational therapy and neurology at Washington University in St. Louis.

Falls linked to early Alzheimer's disease 2011

The second is pre-clinical development, where these compounds are tested in cell cultures and lab animals to show compound safety and their activity in the disease.

Azita Ardakani: Online Giving and the Health Landscape Azita Ardakani 2011