Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- adjective
prior tointegration
Etymologies
from Wiktionary, Creative Commons Attribution/Share-Alike License
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Examples
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Haseltine WA (1991) Determination of viral proteins present in the human immunodeficiency virus type 1 preintegration complex.
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After a reverse-transcription step [2], IN becomes part of the preintegration complex (PIC) which also includes the newly obtained viral cDNA, as well as the viral matrix, Vpr, and nucleocapsid proteins
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Following nuclear import of the viral preintegration complex, the host chromosomal DNA becomes accessible to the viral cDNA and the second step of the integration process, namely the strand-transfer step takes place.
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Farnet CM, Bushman FD (1997) Human immunodeficiency virus type 1 preintegration complexes: studies of organization and composition.
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Various stages of the HIV life cycle including pre-entry, preintegration, and postintegration can be targeted by gene therapy to block viral infection and replication.
Naturejobs - All Jobs Joseph S Anderson 2009
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Upon viral challenge, potent preintegration inhibition of HIV-1 infection was achieved in combination vector-transduced cells in both cultured and primary CD34
Naturejobs - All Jobs Joseph S Anderson 2009
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(postentry/preintegration), and a transactivation response element (TAR) decoy
Naturejobs - All Jobs Joseph S Anderson 2009
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Ultimately, a preintegration complex (PIC), capable of nuclear entry, is formed Two key features of nuclear entry are thus: i) the microtubule assisted directional motion, and ii) the sequence of transformations from capsid to preintegration complex.
PLoS ONE Alerts: New Articles Maria R. D'Orsogna et al. 2009
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