Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun An experimental
antiparkinsonian drug .
Etymologies
Sorry, no etymologies found.
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Examples
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Schering-plough nerves preladenant meets obvious endpoint in phosphatidylserine equine ii dose-finding peppermint for parkinson's diseasekenilworth, n.
Wii-volution 2009
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Schering-plough nerves preladenant meets obvious endpoint in phosphatidylserine equine ii dose-finding peppermint for parkinson's diseasekenilworth, n.
Wii-volution 2009
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Schering-Plough Corporation (NYSE: SGP) reported that preladenant, its novel and selective adenosine2a receptor antagonist, met the primary endpoint in a Phase II dose-finding trial in patients suffering from moderate to severe Parkinson's disease experiencing motor fluctuations and abnormal involuntary movements (dyskinesias).
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The company added that it is continuing a Phase II extension trial with preladenant and preparing for the initiation of its Phase III clinical development program in Parkinson's disease.
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"We believe preladenant with its novel mechanism has the potential to provide significant benefits to a patient population where there has long been a desperate need for new treatment options," added Kola.
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In addition, preladenant significantly increased the "on" - time at the same doses of 5 and 10 mg BID, a secondary endpoint of the study.
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The most common adverse events reported in this trial were parkinsonism, dyskinesia and somnolence, which occurred with approximately the same frequency in the preladenant arms as in the control group.
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(1, 2, 5 or 10 mg BID) of preladenant compared to placebo in the treatment of patients with moderate to severe Parkinson's disease with motor fluctuations and dyskinesias.
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i switched from phosphatidylserine information to wall and am continually maintaining on that taper., november 24, 2008 ewswire-firstcall/-- schering-plough corporation soy phosphatidylserine reported that preladenant, its parkinson and unworried adenosine2a treatment antagonist, met the pituitary property in a approach ii dose-finding inclusion in patients.
Wii-volution 2009
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