Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun A weak
pulse (stimulus ) that inhibits a reaction to a subsequent stronger one
Etymologies
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Examples
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Recently, it has been shown that ceftriaxone (CEF) - induced GLT-1 upregulation is associated with an impairment of the prepulse inhibition (PPI) of the startle reflex, a simple form of information processing that is reduced in schizophrenia, and determines a strong reduction in hippocampal metabotropic glutamate receptor (mGluR) 2
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Petryshen TL, Kirby A, Hammer RP Jr, Purcell S, Singer JB, et al. (2005) Two QTLs for prepulse inhibition of startle identified on mouse chromosome 16 using chromosome substitution strains.
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Anokhin AP, Heath AC, Myers E, Ralano A, Wood S (2003) Genetic influences on prepulse inhibition of startle reflex in humans.
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Willott JF, Tanner L, O'Steen J, Johnson KR, Bogue MA, et al. (2003) Acoustic startle and prepulse inhibition in 40 inbred strains of mice.
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Goulet M, Rusche J, Boismenu R, Davis M (2005) Partial reversal of phencyclidine-induced impairment of prepulse inhibition by secretin.
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Geyer MA, Swerdlow NR (2001) Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies.
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Zarate JM, Rouleau GA, Skamene E, Boksa P (2002) Provisional mapping of quantitative trait loci modulating the acoustic startle response and prepulse inhibition of acoustic startle.
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Vendruscolo LF, Terenina-Rigaldie E, Raba F, Ramos A, Takahashi RN, et al. (2006) A QTL on rat chromosome 7 modulates prepulse inhibition, a neuro-behavioral trait of ADHD, in a Lewis x SHR intercross.
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Krebs-Thomson K, Braff DL, Swerdlow NR (2001) Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review.
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Breen LL, Flodman P, Conti LH, Spence MA, et al. (2003) Identification of quantitative trait loci for prepulse inhibition in rats.
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