Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun An early non-selective
beta blocker clinical candidate , never used clinically due tocarcinogenicity in mice.
Etymologies
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Examples
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Modeling his potential drugs after chemicals known to bind to the beta receptor, his team in 1962 developed a drug called pronethalol that relaxed the heart.
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Using the isoprenaline molecule as a basis Black and coworkers succeeded in developing the first clinically useful beta-receptor antagonists pronethalol (1962) and propranolol (1964).
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Sir James's discovery of the drugs propranolol and pronethalol which work by blocking the body's own response to stress hormones in the early 1960s revolutionized the way doctors helped heart patients.
Media Newswire media-newswire.com 2010
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