Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun organic chemistry Any of a class of alkaloids, found in many plants, that are hepatotoxic

Etymologies

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Examples

  • And some preparations might also contain certain chemicals, called pyrrolizidine alkaloids PAs, that can harm the liver and lungs.

    Herbal hay fever remedies to watch out for 2008

  • And some preparations might also contain certain chemicals, called pyrrolizidine alkaloids (PAs), that can harm the liver and lungs.

    Herbal hay fever remedies to watch out for 2008

  • One important subgroup in this category is that known as the pyrrolizidine alkaloids.

    Chapter 4 1994

  • Some butterbur products contain chemicals called unsaturated pyrrolizidine alkaloids, which can harm the liver.

    Supplements and herbal remedies may ease migraines 2010

  • Her research involved, successively, identification and syntheses of a number of metabolites of carcinogenic and related polycyclic aromatic hydrocarbons (PAHs); simulation in vitro of biological oxidations of PAHs; isolation of carcinogens from shale oil and coal tar; and, from the 1960s, studies on the carcinogenic action of certain pyrrolizidine (Senecio) alkaloids and their ability to induce chronic lesions and tumors in the liver, pancreas, etc., and of diazomethane and certain nitroso compounds.

    Regina Schoental. 2009

  • Comfrey roots contain a higher concentration of pyrrolizidine alkaloids than do the leaves, but both can lead to cirrhosis, liver cancer, and damage to the lungs and other organs.

    The Best Alternative Medicine Dr. Kenneth R. Pelletier 2000

  • Other common plants besides comfrey also contain pyrrolizidine alkaloids, including coltsfoot, liferoot, and borage.

    The Best Alternative Medicine Dr. Kenneth R. Pelletier 2000

  • However, comfrey contains pyrrolizidine alkaloids, which have been associated with death and illness among livestock that graze on them.

    The Best Alternative Medicine Dr. Kenneth R. Pelletier 2000

  • Borage seed oil is now being sold for its gammalinoleic acid GLA content, but borage oils containing more than 0.5 to 1 mcg per gram of pyrrolizidine alkaloids are not considered safe.

    The Best Alternative Medicine Dr. Kenneth R. Pelletier 2000

  • Caution: Comfrey, an herb, contains pyrrolizidine alkaloids, which have been associated with death and illness among livestock that graze on them.

    The Best Alternative Medicine Dr. Kenneth R. Pelletier 2000

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