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Examples
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In the experiment, Dr. Bassler was looking for a drug that would disrupt a bacteria's quorum-sensing system.
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Instead of killing bacteria, Dr. Bassler wants to simply jam their communication lines -- the quorum-sensing mechanism.
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Getty Images The angler fish, above, makes use of bacteria's ability to shine through quorum-sensing.
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In the deep ocean where light is scarce, the angler fish makes clever use of bacteria's ability to shine through quorum-sensing.
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The researchers found that the chemical interfered with the bacteria's quorum-sensing mechanism and prevented infected worms from dying.
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Thibault FM, Gauthier YP, Palencia M, Popoff MY, et al. (2004) The PmlI-PmlR quorum-sensing system in Burkholderia pseudomallei plays a key role in virulence and modulates production of the MprA protease.
PLoS ONE Alerts: New Articles Chakrit Sawasdidoln et al. 2010
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Dekimpe V, Deziel E (2009) Revisiting the quorum-sensing hierarchy in Pseudomonas aeruginosa: the transcriptional regulator RhlR regulates LasR-specific factors.
PLoS ONE Alerts: New Articles Thomas Bjarnsholt et al. 2010
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Allada G, Schuster M (2009) Instantaneous within-patient diversity of Pseudomonas aeruginosa quorum-sensing populations from cystic fibrosis lung infections.
PLoS ONE Alerts: New Articles Thomas Bjarnsholt et al. 2010
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Riedel K, Hentzer M, Heydorn A, Gotschlich A, et al. (2001) The cep quorum-sensing system of Burkholderia cepacia
PLoS ONE Alerts: New Articles Chakrit Sawasdidoln et al. 2010
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Erwinia carotovora quorum-sensing signaling molecule.
PLoS ONE Alerts: New Articles Chakrit Sawasdidoln et al. 2010
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