Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun A group of genes that is regulated by the same regulatory molecule. The genes of a regulon share a common regulatory element binding site or promoter. The genes comprising a regulon may be located non-contiguously in the genome.

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Examples

  • These results indicate that a Myc regulon, which is activated in proliferating cells during normal development as well as during tumor progression, has primordial roots in the evolution of an inducible growth regime in a protozoan ancestor of animals.

    BioMed Central - Latest articles Michael D Cole and Albert J Erives Seth J Brown 2008

  • As I am presently writing my graduate thesis regarding the regulation of invasion genes in Mycobacterium avium, with heavy references to the Hil regulon in Salmonella part of a pathogenicity island, I should have thought of LGT as an incubator for genetic change within a species.

    The Faith That Dare Not Speak Its Name - The Panda's Thumb 2005

  • Rodionov DA, Mironov AA, Gelfand MS (2002) Conservation of the biotin regulon and the BirA regulatory signal in Eubacteria and Archaea.

    PLoS ONE Alerts: New Articles Vibha Gupta et al. 2010

  • Transcription factors not broadly conserved across the phylum are possibly involved in regulon systems that have diverged between species.

    BioMed Central - Latest articles 2010

  • CM, Husson RN (2008) Regulation of the SigH stress response regulon by an essential protein kinase in

    PLoS ONE Alerts: New Articles Gunjan Arora et al. 2010

  • Rodionov DA, Mironov AA, Gelfand MS (2002) Conservation of the biotin regulon and the BirA regulatory signal in Eubacteria and Archaea.

    PLoS ONE Alerts: New Articles Vibha Gupta et al. 2010

  • Examining binding site enrichment patterns in light of transcription factor conservation patterns suggests a second mode via which regulon systems may diverge - rewiring of existing transcription factors and their associated binding sites in specific ways.

    BioMed Central - Latest articles 2010

  • Even less is known about how regulon systems, consisting of transcription factors and target genes together with their associated biological process, evolve in these diverse parasites.

    BioMed Central - Latest articles 2010

  • Within these systems a third analogous receptor, the QscR operates with 3-oxo-C (12) - HSL to modulate gene expression of a specific regulon which overlaps with the two other

    PLoS ONE Alerts: New Articles Thomas Bjarnsholt et al. 2010

  • Rodionov DA, Mironov AA, Gelfand MS (2002) Conservation of the biotin regulon and the BirA regulatory signal in Eubacteria and Archaea.

    PLoS ONE Alerts: New Articles Vibha Gupta et al. 2010

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