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- noun biochemistry A
single-stranded DNA transesteraseproduced by some prokaryotesand viruses
Sorry, no etymologies found.
Exactly how bisphosphonates destroy each bacterium is still unknown, Redinbo said, but the drugs are potent, wiping out any E. coli carrying relaxase. “That it killed bacteria was a surprise,” he said.
Led by graduate student Scott Lujan, the team suspected they could block relaxase by searching for vulnerability in a three-dimensional picture of the relaxase protein.
The drugs, called clodronate and etidronate, steal the DNA binding site, preventing relaxase from handling DNA.
Many highly-drug resistant bacteria rely on an enzyme, called DNA relaxase, to obtain and pass on their resistance genes.
The researchers analyzed relaxase because it plays a crucial role in conjugation.
DNA/relaxase complex to the nucleus of cultivated colonic epithelial cells will be visualised by confocal fluorescence imaging.
One of the major contributors to this phenomenon is the VirD2 relaxase protein that recognises, binds and cleaves the border sequence of the
The project aims at identifying the sequence (s) recognised by each relaxase using the