Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun A protease-inhibiting drug given in the form of its mesylate, used usually in combination with other drugs to suppress the replication of HIV.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun pharmacology An anti-retroviral drug of the protease inhibitor class that is used in to treat HIV infected patients.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • noun a weak protease inhibitor (trade name Invirase) used in treating HIV

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[saquin- (perhaps alteration of (i)soquin(oline) : iso– + quinoline) + a(nti)vir(al).]

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Examples

  • The new era in treatment started last December, when Hoffman-La Roche introduced saquinavir (brand name Invirase), and it took off in March with the arrival of Merck's indinavir (Crixivan) and Abbott Laboratories 'ritonavir (Norvir).

    Targeting A Deadly Scrap Of Genetic Code 2008

  • In September 1995, Howley started on a new combination of drugs, including two that had just been rushed onto the market, Norvir and saquinavir.

    The End Of Aids? 2008

  • They found that serum taken from people who were taking antiretroviral therapy - which included ritonavir-boosted saquinavir (Invirase) or lopinavir (Kaletra) - showed significant antimalarial activity.

    ANC Daily News Briefing 2006

  • Garlic supplements, it says, have been shown to induce drug-nutrient interactions including "sharply reduced" blood levels of the antiviral medication saquinavir.

    ANC Daily News Briefing 2003

  • Rifampin and saquinavir should not be taken together with Norvir.

    WebWire | Recent Headlines 2010

  • People should tell their doctor if they are taking rifampin and saquinavir.

    WebWire | Recent Headlines 2010

  • Both drugs, Invirase (saquinavir) and Norvir (ritonavir), are in the family of HIV medications known as protease inhibitors.

    StarTribune.com rss feed 2010

  • People should tell their doctor if they are taking rifampin and saquinavir.

    BioSpace.com Featured News and Stories 2010

  • Rifampin and saquinavir should not be taken together with Norvir.

    BioSpace.com Featured News and Stories 2010

  • People should tell their doctor if they are taking rifampin and saquinavir.

    BioSpace.com Featured News and Stories 2010

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