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selegiline

Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun A drug, C13H17N, that is an irreversible inhibitor of a specific type of monoamine oxidase, used in its hydrochloride form in conjunction with levodopa and carbidopa to treat patients with Parkinson's disease.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun A drug used for the treatment of early-stage Parkinson's disease, depression and senile dementia.

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[Probably sele(ctive) (from its being a selective monoamine oxidase inhibitor) + alteration of (par)gyline, a closely related drug (ultimately from Latin arg(entum), silver; see arg- in Indo-European roots from the fact that one of the constituents of pargyline was discovered in a precipitate containing silver + –yl + –ine).]

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Examples

  • And the pill-switching went on for several years nationwide, including other prescriptions: generic Prozac (fluoxetine) for depression, and generic Eldepryl (selegiline) for Parkinson's.

    Walgreens Pill-Flipping Scheme Costs Taxpayers Millions - The Consumerist 2008

  • Eldepryl (selegiline), a medication used to treat Parkinson�s disease, was found to induce very high blood pressure.

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  • As a local retail pharmacist, I send faxes to confirm doses &/or missing strengths all the time - but never send a pt without a drug unless its a sertraline/selegiline kind of interaction & the pt says he thinks he's supposed to take both.

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  • The survival rate of 341 patients with moderately severe Parkinson's who were given the drug selegiline together with 2,000 IUs of vitamin E daily survived 230 days, compared to only 145 days' survival for patients who took only the drug plus placebo.

    THE NATURAL REMEDY BIBLE JOHN LUST 2003

  • Because Emsam is a patch that delivers the MAOI selegiline through the skin, it avoids the medication passing through the stomach -- which was the danger area for problematic interactions with foods that contain a chemical called tyramine.

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