semaglutide

This is far lower than that seen with semaglutide, the drug in medications like Ozempic and Wegovy.

Daily pill could replace weight-loss shots like Ozempic and Wegovy Grace Wade 2025

In clinical trials, 40 weeks of semaglutide treatment led to a roughly 14 per cent reduction in body weight in people who were overweight or had obesity.

Daily pill could replace weight-loss shots like Ozempic and Wegovy Grace Wade 2025

They found that 62.9 per cent of those taking semaglutide had marked reductions in liver fat and inflammation, compared with 34.3 per cent of the placebo group.

Drugs like Wegovy can be effective at treating fatty liver disease Christa Lesté-Lasserre 2025

Doctors prescribed each participant a weekly injection of either semaglutide or a placebo to take for four and a half years.

Drugs like Wegovy can be effective at treating fatty liver disease Christa Lesté-Lasserre 2025

In a trial in 2020 involving 320 people, Newsome and his colleagues found that a daily semaglutide injection led to reduced liver fat and inflammation in 59 per cent of those with MASH.

Drugs like Wegovy can be effective at treating fatty liver disease Christa Lesté-Lasserre 2025

Feed Me secreted leptin to simulate fullness and blocked the release of ghrelin, which promotes hunger; in another variety, Sate Me, the living implant produced semaglutide drugs such as Mounjaro, Wegovy and Ozempic to remove the desire to eat or drink.

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“Both are major drivers of ageing in many different types of cells.” However, he believes much of this benefit stems not from semaglutide’s direct effect on cells, but from broader improvements to overall health. Whether we should all be taking semaglutide to stay biologically younger remains to be seen. “Prescribing it more broadly as an anti-ageing therapy is premature,” says Dwaraka.

Ozempic really could turn back the clock on your biological age Helen Thomson 2025

“Those on semaglutide became, on average, 3.1 years biologically younger by the end of the study,” says Dwaraka. Those in the placebo group showed no significant change. “Semaglutide may not only slow the rate of ageing, but in some individuals partially reverse it,” he says.

Ozempic really could turn back the clock on your biological age Helen Thomson 2025

GLP-1 drugs like Ozempic and Wegovy, both of which contain the medication semaglutide, have gained huge prominence for their effects on obesity, but are also being explored for conditions such as cardiovascular disease, addiction and dementia.

Ozempic really could turn back the clock on your biological age Helen Thomson 2025

Although the results were in people with HIV-associated lipohypertrophy, many of the biological pathways affected by semaglutide weren’t specific to HIV pathology.

Ozempic really could turn back the clock on your biological age Helen Thomson 2025