Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun A despicable or disgusting person.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun slang A person who is slimy (in the figurative sense of underhanded, sneaky).

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[slime + -ball (probably as in oddball).]

from Wiktionary, Creative Commons Attribution/Share-Alike License

slime + ball

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